High-Sensitivity CRP

hs-CRP is a high-sensitivity measure of C-reactive protein, a liver-made protein that rises with inflammation. The high-sensitivity assay can detect the low-grade inflammation relevant to cardiovascular risk.

Chronic low-grade inflammation contributes to atherosclerosis, and hs-CRP adds independent information to cholesterol-based risk. It is non-specific, however — many things raise it — so it is interpreted alongside the broader picture.

1. 1

   FoundationCardiovascular HealthThe best place to understand what actually prevents heart disease.
2. 2

   ConditionAtherosclerotic Cardiovascular DiseaseThe disease behind most heart attacks and strokes
3. 3

   Signal RecordOmega-3 Fatty AcidsFish Oil / EPA + DHA
4. 4

   Body SystemCardiovascularHeart function, blood pressure, and circulatory health.
5. 5

   BiomarkerApolipoprotein BThe atherogenic particle-count marker

1. Measure it
2. Understand your result
3. See what raises and lowers it
4. Apply evidence-based interventions
5. Recheck on your review cadence

An orientation to how this topic is typically approached — not medical advice.

A persistently elevated hs-CRP (with acute causes excluded) suggests ongoing inflammation and can refine cardiovascular risk, particularly when other factors are borderline. It does not identify the source of inflammation.

• High-sensitivity blood assay
• Best measured when free of acute illness; repeat to confirm

hs-CRP predicts cardiovascular events independently of cholesterol, and a landmark trial showed benefit from statin therapy in people selected partly by elevated hs-CRP — though it remains a non-specific marker.

• AHA/CDC Scientific Statement on inflammation markers
• 2018 ACC/AHA Cholesterol Guideline (risk-enhancing factors)

Sources are named authoritative guidelines and scientific bodies. Biomarker pages present established clinical context; calibrated evidence verdicts on specific interventions live in the linked Signal Records.