Blood Pressure
The most impactful modifiable vital sign
Overview
Blood pressure is the force of blood against artery walls, reported as systolic over diastolic (mmHg). It is a vital sign rather than a lab test, but one of the most powerful and modifiable predictors of health.
Why it matters
High blood pressure is a leading cause of heart attack, stroke, heart failure, kidney disease, and dementia, and it is causal — lowering it reduces events. Because it is often symptomless, measurement is the only way to know.
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How this usually unfolds
- Measure it
- Understand your result
- See what raises and lowers it
- Apply evidence-based interventions
- Recheck on your review cadence
Where the evidence points
Normal < 120/80; elevated 120–129/<80; stage 1 hypertension 130–139 or 80–89; stage 2 ≥ 140 or ≥ 90 mmHg (US thresholds).
Diagnosis relies on proper technique and repeated or out-of-office (home/ambulatory) readings, not a single measurement.
Clinical interpretation
Sustained readings above target raise cardiovascular and kidney risk. Isolated high readings may reflect 'white-coat' effect; home monitoring clarifies. Very high readings with symptoms are a medical emergency.
What raises and lowers it
Raises it
- High sodium intake
- Excess weight
- Alcohol
- Physical inactivity and stress
- Aging and genetics
Lowers it
- The DASH dietary pattern
- Sodium reduction
- Weight loss
- Regular aerobic exercise
- Reduced alcohol; antihypertensive medication (clinician-directed)
How this connects across BioSignal
Related Foundations
Related Signal Records
Related peptides
Related peptide families
Related biomarkers
Related comparisons
Related body systems
Related conditions
Related pharmaceuticals
Related lifestyle interventions
Diagnostics
- Validated cuff; correct size and technique
- Home and ambulatory monitoring for diagnosis
Frequently asked questions
Which number matters more, top or bottom?
Both matter; systolic (the top number) generally predicts risk better after midlife. Consistent elevation of either warrants attention.
Is one high reading a problem?
Not necessarily — stress, caffeine, or technique can spike a single reading. Diagnosis relies on repeated measurements, ideally at home.
Evidence summary
That lowering elevated blood pressure reduces cardiovascular and kidney events is established by large randomized trials across drug classes and lifestyle interventions.
References & sources
- 2017 ACC/AHA High Blood Pressure Guideline
- 2023 ESH Guidelines for Arterial Hypertension
- DASH and SPRINT trials
Educational information — not medical advice
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