Fasting Glucose
Blood sugar after an overnight fast
Overview
Fasting plasma glucose is the blood sugar level after at least eight hours without food. It is a simple, widely used snapshot of glucose regulation.
Why it matters
Fasting glucose is a core screening test for prediabetes and diabetes and an early signal of insulin resistance. Paired with fasting insulin, it gives a fuller picture of metabolic health than either alone.
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How this usually unfolds
- Measure it
- Understand your result
- See what raises and lowers it
- Apply evidence-based interventions
- Recheck on your review cadence
Where the evidence points
< 100 mg/dL normal; 100–125 mg/dL prediabetes; ≥ 126 mg/dL diabetes (confirmed).
A single value can be affected by stress, illness, sleep, and the dawn phenomenon; diagnosis needs confirmation.
Clinical interpretation
Rising fasting glucose reflects the liver and muscles handling glucose less well. It often climbs later than fasting insulin, so a 'normal' glucose with high insulin can still indicate early insulin resistance.
What raises and lowers it
Raises it
- Insulin resistance
- Poor sleep and stress
- Physical inactivity
- The dawn phenomenon (morning cortisol)
Lowers it
- Weight loss and activity
- Carbohydrate quality
- Improved sleep
- Metformin and other glucose-lowering therapy (clinician-directed)
How this connects across BioSignal
Related Foundations
Related peptides
Related peptide families
Related comparisons
Related body systems
Related conditions
Related pharmaceuticals
Related lifestyle interventions
Diagnostics
- Fasting blood draw (≥ 8 hours)
- Often paired with fasting insulin for HOMA-IR
Frequently asked questions
Why is my morning glucose higher than before bed?
The dawn phenomenon — a natural morning rise in cortisol and glucose — can raise fasting readings, especially with insulin resistance. It's one reason HbA1c and trends matter more than a single number.
Evidence summary
Fasting glucose is a long-established diagnostic criterion; its thresholds are standardized and well validated for diabetes and prediabetes.
References & sources
- ADA Standards of Care in Diabetes
- WHO diagnostic criteria for diabetes
Educational information — not medical advice
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